张凌飞

2024年09月10日 09:51    点击:[]



张凌飞


职称:助理研究员


邮箱:lingfeizhang@sibcb.ac.cn


教育经历

2016.9-2020.7  复旦大学基础医学院 博士

2012.9-2015.7 中国科学院分子细胞科学卓越创新中心 硕士

2006.9-2010.6  华东理工大学 学士


研究经历

2010.10-2012.9 中国科学院分子细胞科学卓越创新中心 助理实验师

2020.12-2023.6 国科大杭州高等研究院生命与健康科学学院 博士后

2023.6 -至今 国科大杭州高等研究院生命与健康科学学院 助理研究员


研究方向

RNA以及RNA 结合蛋白在男性不育和肿瘤发生中的功能


科研项目

中国博士后科学基金会博士后面上资助二等


发表论文

Zhao, Ming-Na, Ling-Fei Zhang (co-first author), Zhen Sun, Li-Hua Qiao, Tao Yang, Yi-Zhe Ren, Xian-Zhou Zhang, Lei Wu, Wen-Li Qian, Qiao-Mei Guo, Wan-Xing Xu, Xue-Qing Wang, Fei Wu, Lin Wang, Yutong Gu, Mo-Fang Liu* and Jia-Tao Lou* (2023). "A novel microRNA-182/Interleukin-8 regulatory axis controls osteolytic bone metastasis of lung cancer." Cell Death & Disease 14(5).


Chen, Hong, Ling-Fei Zhang (co-first author), Lu Zhang, Ying Miao, Yun Xi, Mo‐Fang Liu, Min Zhang* and Biao Li *(2023). "CircANKRD17 promotes glycolysis by inhibiting miR‐143 in breast cancer cells." Journal of Cellular Physiology 238(12): 2765-2777.


Ling-Fei Zhang., W. J. Tan-Tai, X. H. Li, M. F. Liu, H. J. Shi, P. A. Martin-DeLeon, W. S. O* and H. Chen* (2020). "PHB regulates meiotic recombination via JAK2-mediated histone modifications in spermatogenesis." Nucleic Acids Res 48(9): 4780-4796.


Lou, Jiatao, LingFei Zhang (co-first author), Shaogang Lv, Chenzi Zhang and Shuai Jiang* (2017). "Biomarkers for Hepatocellular Carcinoma." Biomarkers in Cancer 9.


Ling-fei Zhang, Shuai Jiang* and Mo-Fang Liu *(2017). "MicroRNA regulation and analytical methods in cancer cell metabolism." Cellular and Molecular Life Sciences 74(16): 2929-2941.


Zhao, Mingna, Lingfei Zhang, Shaogang Lv, Chenzi Zhang, Lin Wang, Hong Chen, Yan Zhou* and Jiatao Lou* (2017). "IQGAP1 Mediates Hcp1-Promoted Escherichia coli Meningitis by Stimulating the MAPK Pathway." Frontiers in Cellular and Infection Microbiology 7.


Miao, Ying, Ling-fei Zhang, Rui Guo, Sheng Liang, Min Zhang, Shuo Shi, Cheng-fang Shang-Guan, Mo-fang Liu and Biao Li* (2016). "18F-FDG PET/CT for Monitoring the Response of Breast Cancer to miR-143-Based Therapeutics by Targeting Tumor Glycolysis." Molecular Therapy - Nucleic Acids 5.


Wang, Wenshuo, Aikebaier Maimaiti, Yun Zhao, Lingfei Zhang, Hongyue Tao, Hui Nian, Limin Xia, Biao Kong, Chunsheng Wang, Mofang Liu and Lai Wei* (2016). "Analysis of Serum Metabolites to Diagnose Bicuspid Aortic Valve." Scientific Reports 6(1).


Ling-Fei Zhang., J. T. Lou, M. H. Lu, C. Gao, S. Zhao, B. Li, S. Liang, Y. Li, D. Li and M. F. Liu* (2015). "Suppression of miR-199a maturation by HuR is crucial for hypoxia-induced glycolytic switch in hepatocellular carcinoma." Embo j 34(21): 2671-2685.


Wang, Lin, Ling-Fei Zhang (co-first author), Jing Wu, Shu-Jun Xu, Yang-Yang Xu, Dangsheng Li, Jia-Tao Lou* and Mo-Fang Liu* (2014). "IL-1β-Mediated Repression of microRNA-101 Is Crucial for Inflammation-Promoted Lung Tumorigenesis." Cancer Research 74(17): 4720-4730.


Hu, Song, Wei Zhu, Ling-Fei Zhang (co-first author), Ming Pei and Mo-Fang Liu*(2013). "MicroRNA-155 broadly orchestrates inflammation-induced changes of microRNA expression in breast cancer." Cell Research 24(2): 254-257.


Jiang, Shuai, Ling-Fei Zhang (co-first author), Hong-Wei Zhang, Song Hu, Ming-Hua Lu, Sheng Liang, Biao Li, Yong Li, Dangsheng Li, En-Duo Wang* and Mo-Fang Liu* (2012). "A novel miR-155/miR-143 cascade controls glycolysis by regulatinghexokinase 2in breast cancer cells." The EMBO Journal 31(8): 1985-1998.






国科大杭州高等研究院生命与健康科学学院

浙江省杭州市西湖区象山支弄1号

电话:0571-86088036