教育经历

2006.09 – 2011.12  湖南大学（化学/生物传感与计量学国家重点实验室）博士研究生 导师：姚守拙院士

2002.09 – 2006.06  湖南师范大学，学士学位

工作经历

2024.03 – 至今 国科大杭州高等研究院环境学院 研究员

2014.11 – 2024.02  浙江省农业科学院农产品质量安全与营养研究所，研究员/研究室主任

2018.12 – 2019.12  美国杜克大学机械工程学院，访问学者 （合作导师：Tony Jun Huang）

2016.11 – 2016.12  美国威斯康星大学麦迪逊分校农业与生命科学学院，访问学者（合作导师：Sundaram Gunasekaran）

2012.03 – 2014.09  浙江大学生物系统工程与食品科学学院，助理研究员

社会任职

中国农学会理事

获奖及荣誉

1. 2023年，中国分析测试协会科学技术CAIA奖一等奖（2/8）

2. 2023年，丽水中药全产业链省级专家服务示范团成员

3. 2022年，获浙江省自然科学基金杰出青年项目资助

4. 2022年，浙江省农业科学院青年英才“杰出青年”

5. 2021年，浙江省省级青年拔尖人才

6. 2021年，受聘为浙江农艺师学院专业导师

7. 2019年，浙江省农业科学院“青年新锐”

8. 2019年，浙江省农业科学院“科技创新标兵”

9. 2018年，国家农业农村部杰出青年农业科学家

10. 2014年，湖南省优秀博士学位论文奖

11. 2012年，ISBBN国际会议学术海报一等奖

12. 2010年，湖南大学优秀研究生干部

13. 2009年，湖南大学优秀研究生

14. 2006年，湖南省优秀毕业生

15. 2004年，湖南师范大学首届贵联优秀学生干部

承担科研项目

1. 国家自然科学基金面上项目，32072303，食品中危害因子的一体化声流控分离-富集-灵敏检测原理与技术，（2021/01–2024/12），58万元，主持。

2. 国家自然科学基金面上项目，31671940，三维超稳纳米复合材料增敏的农兽药残留快速识别与现场检测技术研究，（2017/01-2020/12），63万元，已结题，主持。

3. 国家自然科学基金青年基金，21205106，基于多功能多肽的蛋白激酶活性动态传感与应用，（2013/01-2015/12），25万元，已结题，主持。

4. 国家引智重点项目，20173300011，新材料增敏的农产品中农兽药残留快速检测技术研究，（2017/01-2017/12），20万元，已结题，主持。

5. 浙江省杰出青年项目，LR22C200006，农产品中食源致病菌的特异识别与即时检测（2022/01-2024/12），80万元，主持。

6. 浙江省重点研发项目，2021C02062，食用农产品高风险危害因子高效富集-快速检测关键技术与智能化产品研发（2021/01-2023/12），230万元，主持。

7. 浙江省农业厅例行监测项目，2015年葡萄、柑橘、猕猴桃质量安全专项监测，（201501-201512），42.75万元，已结题，主持。

8. 浙江省农业科学院国重室自主设计课题，基于传感识别的农产品中农兽药残留现场快速检测技术研究，（201901-202112），100万元，已结题，主持。

9. 浙江省农业科学院产业化资金项目，高灵敏荧光农残速测卡研制，（2018/01-2018/12），30万，已结题，主持。

10. 浙江省农业科学院国际合作项目，基于纳米金比色传感技术的食品中有毒有害物快速检测研究，（2016/01-2016/12），11万，已结题，主持。

代表论著

1. Xiaoyun Qu*, Yaping Hu, Chenggang Xu, Yue Li, Lin Zhang, Qiao Huang, Sareh Sadat Moshirian-Farahi, Jianmin Zhang, Xiahong Xu*, Ming Liao, Yingchun Fu*, Optical sensors of volatile organic compounds for non-invasive diagnosis of diseases, Chemical Engineering Journal, 2024, 485, 149804.

2. Jingrui Yuan, Liu Wang, Liang Huang, Kaiyu He, Hongmei Wang, Xiahong Xu*, Bin Su*, and Jing Wang*. CRISPR–Cas12a-Mediated Hue-Recognition Lateral Flow Assay for Point-of-Need Detection of Salmonella, Analytical Chemistry, 2024, 96, 1, 220–228

3. Kaiyu He, Haoran Quan, Liu Wang, Jing Zhang, Hongmei Wang, Xiaohua Zhu, Xiahong Xu*. Engineering cotton fibers with zirconium metal-organic frameworks as a recyclable material for sensing and removing aflatoxins in water. Sensors and Actuators B: Chemical, 2023, 397, 134673.

4. Yue Li, Xinyue Ma, Wenyue Zhu, Qiao Huang, Yameng Liu, Jinming Pan, Yibin Ying, Xiahong Xu,* Yingchun Fu*. Enzymatic Catalysis in Size and Volume Dual-Confined Space of Integrated Nanochannel-Electrodes Chip for Enhanced Impedance Detection of Salmonella, Small, 2023, 2300900.

5. Tongtong Ma, Jie Zhang, Lin Zhang, Qi Zhang, Xiahong Xu,* Yonghua Xiong, Yibin Ying, Yingchun Fu*. Recent advances in determination applications of emerging films based on nanomaterials, Advances in Colloid and Interface Science, 2023, 311, 102828.

6. Liu Wang, Linlin Bai, Hongmei Wang, Kaiyu He, Rui Wang, Qiang Wang*, Fang Zhang*, Xiahong Xu*. Graphene oxide assisting the visual detection of Salmonella by CRISPR/Cas12a. Microchemical Journal, 2023, 191, 108870.

7. 俞静, 姚志豪, 何开雨, 邢丙聪, 王强, 程科军, 王柳, 徐霞红. 基于纳米材料的光学生物传感器在中药真菌毒素检测中的应用. 分析化学. 2023, 51(4), 472~483.

8. 李上上；王洪梅；何开雨；王柳；蓝航镇*；徐霞红*. MXene材料在重金属电化学检测应用中的研究进展, 复合材料学报, 2023, 42(0): 1-14.

9. Pengzhan Liu, Zhenhua Tian*, Kaichun Yang, Ty Downing Naquin, Nanjing Hao, Huiyu Huang, Jinyan Chen, Qiuxia Ma, Hunter Bachman, Peiran Zhang, Xiahong Xu*, Junhui Hu*, and Tony Jun Huang*. Acoustofluidic black holes for multifunctional in-droplet particle manipulation, Science Advances, 2022, 8, eabm2592.

10. Liu Wang, Fang He, Xueyun Chen, Kaiyu He, Linlin Bai, Qiang Wang, Fang Zhang*, Xiahong Xu*, A CRISPR/Cas12a-based label-free fluorescent method for visual signal output, Sensors and Actuators B: Chemical, 2022, 370, 132368.

11. Linlin Bai^#, Liu Wang^#, Shuqin Huang, Rong Bai, Xucong Lv, Liping Sun, Fang Zhang*, and Xiahong Xu*. Rapid, Visual, and Sequence-Specific Detection of Salmonella in Egg Liquid with vis-NEAA, a CRISPR/Cas12 Empowered New Strategy. Journal of Agricultural and Food Chemistry, 2022, 70: 2401-2409.

12. Kaiyu He^#, Liping Sun^#, Liu Wang, Wang Li, Guixian Hu, Xiaofeng Ji, Yiming Zhang*, Xiahong Xu*. Engineering DNA G-quadrulex Assembly for Label-free Detection of Ochratoxin A in Colorimetric and Fluorescent Dual Modes. Journal of Hazardous Materials, 2022, (423) 126962.

13. Liu Wang; Kaiyu He; Xinquan Wang; Qiang Wang; Haoran Quan; Peilong Wang*; Xiahong Xu*; Recent progress in visual methods for aflatoxin detection, Critical Reviews in Food Science and Nutrition, 2022 (62): 77849-7865.

14. Xueyun Chen#, Liu Wang#, Fang He, Ganghui Chen, Linlin Bai, Kaiyu He, Fang Zhang*, and Xiahong Xu*, Label-Free Colorimetric Method for Detection of Vibrio parahaemolyticus by Trimming the G-Quadruplex DNAzyme with CRISPR/Cas12a, Analytical Chemistry, 2021, 93, 14300-14306.

15. Zhishang Li^#, Xiahong Xu^#, Haoran Quan, Jie Zhang, Qi Zhang, Yingchun Fu*, Yibin Ying, Yanbin Li*, Adsorptive and responsive hybrid sponge of melamine foam and metal organic frameworks for rapid collection/removal and detection of mycotoxins, Chemical Engineering Journal, 2021, 410(1): 0-128268.

16. Liu Wang, Kaiyu He, Omer Sadak, Xinquan Wang^*, Qiang Wang, Xiahong Xu^*. Visual detection of in vitro nucleic acid replication by submicro- and nano-sized materials. Biosensors and Bioelectronics, 2020, 169, 112602-112615.

17. Liu Wang, Kaiyu He, Haoran Quan, Xinquan Wang, Qiang Wang, Xiahong Xu*. A luminescent method for detection of parathion based on zinc incorporated metal-organic framework, Microchemical Journal, 2020, 153, 104441-104447.

18. Kaiyu He, Zhishang Li, Liu Wang, Yingchun Fu, Haoran Quan, Yanbin Li^*, Xinquan Wang, Sundaram Gunasekaran, Xiahong Xu^*, A Water-stable Luminescent Metal-organic Framework for Rapid and Visible Sensing of Organophosphorus Pesticides, ACS Applied Materials & Interfaces, 2019, 11(29), 26250-26260.

19. Kaiyu He, Hua Yang, Liu Wang, Jiehao Guan, Min Wu, Hongmei He, Sundaram Gunasekaran, Xinquan Wang, Qiang Wang, Xiahong Xu^*. A universal platform for multiple logic operations based on self-assembled a DNA tripod and graphene oxide. Chemical Engineering Journal, 2019 (368), 877–887.

20. Zhishang Li^#, Xiahong Xu^#, Yingchun Fu, Yuna Guo, Qiaoyan Zhang, Hua Yang* and Yanbin Li*. water-stable luminescent metal-organic framework for effective detection of Aflatoxin B1 in walnut and almond beverages, RSC Advance, 2019, 9, 620-625.

21. Xiahong Xu, Yuna Guo, Liu Wang, Kaiyu He, Yirong Guo, Xin Quan Wang, and Sundaram Gunasekaran. Hapten-Grafted Programmed Probe as Corecognition Element for Competitive Immunosensor to Detect Acetamiprid Residue in Agricultural Products, Journal of Agricultural and Food Chemistry, 2018, 66 (29), 7815–7821.

22. Xiahong Xu, Yuna Guo, Xiangyun Wang, Wang Li, Peipei Qi, Zhiwei Wang, Xinquan Wang*, Sundaram Gunasekaran and Qiang Wang, Sensitive Detection of Pesticides by a Highly Luminescent Metal-organic Framework, Sensors and Actuators B: Chemical, 2018, 260, 339-345.

23. Hua Yang, Xin Qi, Xinquan Wang, Xiangyun Wang, Qiang Wang, Peipei Qi, Zhiwei Wang, Xiahong Xu^*, Yingchun Fu^*, Shouzhuo Yao. Regulating Immobilization Performance of Metal-organic Coordination Polymers through Pre-coordination for Biosensing. Analytica Chimica Acta, 2018, 1005, 27-33.

24. Xiahong Xu, Yuwei Yuan, Guixian Hu, Xiangyun Wang, Peipei Qi, Zhiwei Wang, Qiang Wang^*, Xinquan Wang^*, Yingchun Fu, Yanbin Li, Hua Yang. Exploiting pH-Regulated Dimer-Tetramer Transformation of Concanavalin A to Develop Colorimetric Biosensing of Bacteria. Scientific Reports, 2017, 7: 1452.

25. Xiahong Xu, Xin Qi, Xinquan Wang, Xiangyun Wang, Qiang Wang, Hua Yang^*, Yingchun Fu^*, Shouzhuo Yao. Highly Efficient Enzyme Immobilization by Nanocomposites of Metal Organic Coordination Polymers and Carbon Nanotubes for Electrochemical Biosensing. Electrochemistry Communications, 2017, 79, 18-22.

26. 徐霞红，权浩然，何开雨，王柳，王新全，王强。农田环境中农药残留的比例型荧光传感研究, 农业机械学报，2020, 51（11） 229-234.

27. 徐霞红，韩芳芳，傅迎春^*，王新全，王祥云，姚守拙. 生物/化学同步聚合法制备纤维蛋白纳米复合物及传感研究, 分析科学学报, 2017, 33 (3) 302-306.

28. 徐霞红，郭玉娜，王新全，王祥云，齐沛沛，汪志威. 多孔金属有机骨架化合物：PCN 222对农残酶抑制法的增敏研究, 农业机械学报，2017, 5 193-198.

29.  Qinqin Hu, Yingchun Fu, Xiahong Xu^*, Zhaohui Qiao, Ronghui Wang, Ying Zhang, Yanbin Li^*, A colorimetric detection of acrylamide in potato chips based on nucleophile-initiated thiol-ene Michael addition, Analyst, 2016, 141(3):1136-1143.

30. Chunyang Lei^#, Xiahong Xu^#, Jiang Zhou, Xin Liu, Zhou Nie^*, Meng Qing, Pei Li, Yan Huang^*, Shouzhuo Yao, A mix-and-read fluorescence strategy for the switch-on probing of kinase activity based on an aptameric-peptide/graphene-oxide platform. Chemistry–An Asian Journal, 2014, 9(9): 2560-2567.

31. Jiang Zhou^#, Xiahong Xu^#, Wei Liu, Xin Liu, Zhou Nie^*, Meng Qin, Lihua Nie, Shouzhuo Yao, Graphene Oxide-Peptide Nanocomplex as a Versatile Fluorescence Probe of Protein Kinase Activity Based on Phosphorylation Protection against Carboxypeptidase Digestion, Analytical Chemistry, 2013, 85(12): 5746-5754.

32. Xiahong Xu, Jiang Zhou, Xin Liu, Zhou Nie^*, Meng Qin, Manli Guo, Shouzhuo Yao, Aptameric Peptide for One-Step Detection of Protein Kinase, Analytical Chemistry, 2012, 84(11): 4746-4753.

33. Xiahong Xu, Xin Liu, Zhou Nie^*, Yuliang Pan, Manli Guo, Shouzhuo Yao, Label-Free Fluorescent Detection of Protein Kinase Activity Based on the Aggregation Behavior of Unmodified Quantum Dots, Analytical Chemistry, 2011, 83(1): 52-59.

34. Xiahong Xu, Zhou Nie^*, Jinhua Chen^*, Yingchun Fu, Wang Li, Qinpeng Shen, Shouzhuo Yao, A DNA-based electrochemical strategy for label-free monitoring the activity and inhibition of protein kinase, Chemical Communications, 2009, (45): 6946-6948.

35. Xiahong Xu, Jinhua Chen^*, Wang Li, Zhou Nie^*, Shouzhuo Yao, Surface nanocrystallization of glassy carbon electrode: Application in direct electrochemistry of glucose oxidase, Electrochemistry Communications, 2008, 10(10):1459-1462.