研究方向

新污染物的分析方法，环境行为及风险研究

·新污染物环境赋存和行为研究；

·现代色谱分离技术、质谱技术、蛋白质组学技术、代谢组学（脂质组学）技术在新污染物环境行为及其健康效应研究中的应用。

教育经历

2004.9-2008.6: 浙江大学环境科学系，理学学士，环境科学专业

2008.9-2014.1: 中国科学院大学-中科院生态环境研究中心，理学博士，环境科学专业

2011.1-2011.12: 德国亥姆霍兹慕尼黑研究中心（Helmholtz Zentrum München），博士联合培养，环境科学专业

工作经历

2021.04-至今: 国科大杭州高等研究院，副研究员

2017.01-2021.04: 中国科学院生物物理研究所，高级工程师

2018-2021.04: 中国科学院大学兼职副教授

2019.9-2020.10: 美国国家橡树林实验室（Oak Ridge National Laboratory），访问学者

2014.1-2016.12: 中国科学院生物物理研究所，工程师

2015.9-2015-10: 美国国家卫生研究院（National Institutes of Health, NIH）和美国桑福德-伯纳姆医学研究所(Sanford-Burnham Medical Research Institute)，访学

承担科研项目

1. 国家重点研发项目子任务,高暴露风险储能纳米材料的人群暴露途径和外暴露特征（2024.12-2029.11）,50万元，主持

2. 浙江省领雁科技计划项目，在产园区地下水复合污染智慧监测监管与修复技术及装备研发-在产化工园区地下水符合污染智慧监测监管技术与装备研发（2025.01-2028.12）,15万，子任务主持

3. 杭高院青苗项目，基于细胞外囊泡生物学功能的全氟及多氟化合物肝毒性分子机制探究（2024.10-2027.09）,80万元，主持

4. 杭高院自主教育教学项目，环境健康实验课程教材建设探究（2024.06-2026.05）,10万元，主持

5. 浙江省自然科学基金探索项目，基于人群血浆细胞外囊泡多组学分析技术的全氟化合物健康效应分子机制研究(2023.01-2025.12),10万元，主持

6. 浙江省污染暴露与健康干预重点实验室开放基金项目，细胞外囊泡蛋白质组学技术在全氟化合物负面健康效应机制中的应用研究(2023.04-2025.03)，4万元，主持

7. 国家973计划及攀登计划课题，遗传性血液病新型蛋白质机器及标志物的筛选，（2018.05-2023.04），464万元，参与

8. 横向课题，土壤及植物相关样本多组学定性定量分析, 负责人, 2024.10-2025.01

9. 国家自然科学基金青年科学基金项目，全氟化合物职业暴露人群血浆靶向脂质组研究（2017.01-2019.12），21万元，主持

代表论著

1. Zhu, N. ; Li, Z. ; Yu, Y.; Liu, Z. ; Liang, X. ; Wang, W.; Zhao, J.. Fate of microplastics in soil-water systems: View from free radicals driven by global climate change. Ecotoxicology and Environmental Safety 2025, 295.

2. Li, Y. ; Luo, Y.; Liu, Y.; Li, N.; Huang, K.; Li, L. ; Li, Z.; Han, C.; Zhu, N.*; Wang, Y.; et al. Proteomic insights from extracellular vesicles into the molecular mechanisms of health effects induced by Per- and polyfluoroalkyl substances. Journal of Environmental Sciences 2025, 150, 395-411.

3. Zhu, N.; Li, Y. P.; Jiang, L.; Li, L. X. Y.; Li, Z. G.; Wang, Y. W.; Jiang, G. B. Effects of Forest Filtering and Cold Trapping on Polycyclic Aromatic Hydrocarbons Distribution in Southeast Tibet. Chemical Research in Chinese Universities 2023, 39 (3), 399-407.

4. Li, Z.; Lu, Y.; Chen, T.; He, A.; Huang, Y.; Li, L.; Pan, W.; Li, J.; Zhu, N.*; Wang, Y.; et al. Generation Mechanism of Perfluorohexanesulfonic Acid from Polyfluoroalkyl Sulfonamide Derivatives During Chloramination in Drinking Water. Environmental Science & Technology 2023, 57 (47), 18462-18472.

5. Yu, Y.; Li, Z.; Liu, Y.; Wang, F.; Liu, Y.; Zhao, J.; Li, Y.; Gao, Y.; Zhu, N.*, Roles of plant-associated microorganisms in regulating the fate of Hg in croplands: A perspective on potential pathways in maintaining sustainable agriculture. Science of the Total Environment 2022, 834, 155204.

6. Zhu, N.; Schramm, K. W.; Wang, T.; Henkelmann, B.; Zheng, X.; Fu, J.; Gao, Y.; Wang, Y.; Jiang, G., Lichen, moss and soil in resolving the occurrence of semi-volatile organic compounds on the southeastern Tibetan Plateau, China. Science of the Total Environment 2015，518-519, 328-36.

7. Zhu, N.; Schramm, K. W.; Wang, T.; Henkelmann, B.; Zheng, X.; Fu, J.; Gao, Y.; Wang, Y.; Jiang, G., Environmental fate and behavior of persistent organic pollutants in Shergyla Mountain, southeast of the Tibetan Plateau of China. Environmental Pollution 2014, 191, 166-74.

8. Zhu, N.; Fu, J.; Gao, Y.; Ssebugere, P.; Wang, Y.; Jiang, G., Hexabromocyclododecane in alpine fish from the Tibetan Plateau, China. Environmental Pollution 2013, 181, 7-13.

9. Zhu, N.; Li, A.; Wang, T.; Wang, P.; Qu, G.; Ruan, T.; Fu, J.; Yuan, B.; Zeng, L.; Wang, Y.; Jiang, G., Tris(2,3-dibromopropyl) isocyanurate, hexabromocyclododecanes, and polybrominated diphenyl ethers in mollusks from Chinese Bohai Sea. Environmental science & technology 2012, 46, (13), 7174-81.

10. Liang, X.; Zhong, H.; Johs, A.; Lei, P.; Zhang, J.; Tas, N.; Zhang, L.; Zhao, L.; Zhu, N.; Yin, X.; et al. Light-independent phytoplankton degradation and detoxification of methylmercury in water. Nature Water 2023, 1 (8).

11. Liang, X.; Johs, A.; Abernathy, M. J.; Zhao, J.; Du, H.; Ku, P.; Zhang, L.; Zhu, N.; Yin, X.; Brooks, S.; Zhao, L.; Sarangi, R.; Pierce, E. M.; Gu, B., High methylation potential of mercury complexed with mixed thiolate ligands by Geobacter sulfurreducens PCA. Geochimica et Cosmochimica Acta 2023, 342, 74-83.

12. Liang, X.; Zhu, N.; Johs, A.; Chen, H.; Pelletier, D. A.; Zhang, L.; Yin, X.; Gao, Y.; Zhao, J.; Gu, B., Mercury Reduction, Uptake, and Species Transformation by Freshwater Alga Chlorella vulgaris under Sunlit and Dark Conditions. Environmental science & technology 2022, 56 (8), 4961-4969.

13. He, A.; Liang, Y.; Li, F.; Lu, Y.; Liu, C.; Li, J.; Zhou, Z.; Zhu, N.; Liao, C.; Wang, Y.; Jiang, G., Vital Environmental Sources for Multitudinous Fluorinated Chemicals: New Evidence from Industrial Byproducts in Multienvironmental Matrices in a Fluorochemical Manufactory. Environmental science & technology 2022, 56 (23), 16789-16800.

14. Liu, Y.; Chen, H.; Zhu, N.; Zhang, J.; Li, Y.; Xu, D.; Gao, Y.; Zhao, J., Detection and remediation of mercury contaminated environment by nanotechnology: Progress and challenges. Environmental Pollution 2022, 293, 118557.

15. Li, Z.; Mao, X.; Yu, Y.; Zhu, N.; Liu, H.; Xu, N.; Ren, Z.; Peng, W.; Zhong, J. ; Li, Y..; Gao, Y. ; Zhao, J., Novel Metal-Organic Framework Materials In-Focus Detection and Adsorption Cues for Environmental Pollutants. Reviews of Environmental Contamination and Toxicology 2022, 260 (1).

16. Cui, Y.; Li, M.; Zhu, N.; Cheng, Y.; Lam, S. S.; Chen, J.; Gao, Y.; Zhao, J., Bi-based visible light-driven nano-photocatalyst: the design, synthesis, and its application in pollutant governance and energy development. Nano Today 2022, 43.

17. Cui, Y.; Lin, C.; Li, M.; Zhu, N.; Meng, J.; Zhao, J., CuWO4/CuS heterojunction photocatalyst for the application of visible-light-driven photodegradation of dye pollutions. J. Alloys Compd. 2022, 893.

18. Liu, Y.; Chen, H.; Zhu, N.; Zhang, J.; Li, Y.; Xu, D.; Gao, Y.; Zhao, J., Detection and remediation of mercury contaminated environment by nanotechnology: Progress and challenges*. Environmental Pollution 2022, 293.

19. Zhang, X.; Qian, X.; Tang, J.; Zhu, N.; Li, Z.; Fu, J.; Li, L.; Wang, Y., Effect of polar/non-polar facets on the transformation of nanoscale ZnO in simulated sweat and potential impacts on the antibacterial activity. Ecotoxicology and Environmental Safety 2022, 246.

20. Zhang, X.; Tang, J.; Zhu, N.; Li, L.; Wang, Y., Water splitting, pollutant degradation and environmental impact using low-index faceted metal-based nanocrystals. A review. Environmental Chemistry Letters 2022, 20 (2), 1035-1045.

21. Li, Y.; Lu, C.; Zhu, N.; Chao, J.; Hu, W.; Zhang, Z.; Wang, Y.; Liang, L.; Chen, J.; Xu, D.; Gao, Y.; Zhao, J., Mobilization and methylation of mercury with sulfur addition in paddy soil: Implications for integrated water-sulfur management in controlling Hg accumulation in rice. Journal of hazardous materials 2022, 430, 128447.

22. Tang, J.; Zhang, X.; Zhu, N.; Li, L.; Wang, Y., Review on Formation, Analysis and Bioeffect of Protein Corona. Asian Journal of Ecotoxicology 2022, 17 (3), 95-110.

23. Li, H.; Bu, D.; Gao, Y.; Zhu, N.; Wu, J.; Chen, X.; Fu, J.; Wang, Y.; Zhang, A.; Jiang, G., Long-range atmospheric transport and alpine condensation of short-chain chlorinated paraffins on the southeastern Tibetan Plateau. J Environ Sci 2021, 99, 275-280.

24. Sun, Y.; Wang, J.; Guo, X.; Zhu, N.; Niu, L.; Ding, X.; Xie, Z.; Chen, X.; Yang, F., Oleic Acid and Eicosapentaenoic Acid Reverse Palmitic Acid-induced Insulin Resistance in Human HepG2 Cells via the Reactive Oxygen Species / JUN Pathway. Genomics Proteomics Bioinformatics 2021.

25. Li, Y.; Zhu, N.; Liang, X.; Zheng, L.; Zhang, C.; Li, Y.; Zhang, Z.; GAO, Y.; Zhao, J.; A comparative study on the accumulation, translocation and transformation of selenite, selenate, and SeNPs in a hydroponic-plant system. Ecotoxicology and Environmental Safety. 2020, 189, 109955.

26. Li, Y.; Zhu, N.; Liang, X.; Bai, X.; Zheng, L.; Zhao, J.; Li, Y.; Zhang, Z. and Gao, Y.; Silica nanoparticles alleviate mercury toxicity via immobilization and inactivation of Hg(II) in soybean (Glycine max). Environmental Science: Nano. 2020, 7, 1807.

27. Zhao, J.; Liang, X.; Zhu, N.; Wang, L.; Li, Y.; Li, Y.; Zheng, L.; Zhang, Z.; Gao, Y., Chai, Z. Immobilization of mercury by nano-elemental selenium and the underlying mechanisms in hydroponic-cultured garlic plant. Environmental Science: Nano. 2020, 7(4): 1115-1125.

28. Sun, L.; Rasmussen P. K.; Bai Y.; Chen X.; Cai T.; Wang J.; Guo X.; Xie Z.; Ding X.; Niu L.; Zhu N.; You X.; Kirpekar F.; Yang F.; Proteomic Changes of Klebsiella pneumoniae in Response to Colistin Treatment and crrB Mutation-Mediated Colistin Resistance. Antimicrob Agents and Chemotherapy. 2020, 64 (6): e02200-19.

29. Li, N.; Zhou, Y.; Wang J.; Niu L.; Zhang Q.; Sun L.; Ding X.; Guo X.; Xie Z.; Zhu N.; Zhang M.; Chen X.; Cai T.; Yang F.; Sequential Precipitation and Delipidation Enables Efficient Enrichment of Low-Molecular Weight Proteins and Peptides from Human Plasma. Journal of Proteome Research. 2020, 19 (8): 3340-3351.

30. Fang, X.; Wang, H.; Han, D.; Xie, E.; Yang, X.; Wei, J.; Gu, S.; Zhu, N.; Yin, X.; Cheng, Q.; Zhang, P.; Dai, W.; Chen, J.; Yang, F.; Yang, H; Linkermann A.; Gu, W.; Min, J.; Wang, F.; Ferroptosis as a target for protection against cardiomyopathy. Proceedings of the National Academy of Sciences of the Unitied States of America. 2019, 116, 2672-2680.

书籍

1. 《细胞外囊泡基础研究与临床应用》，王前，郑磊主编。2019年1月科学出版社

2. 《新型有机污染物的环境行为》，王亚韡，曾力希，杨瑞强，张海燕，朱娜丽，高燕。科学出版社。