教育经历

2008.09-2013.06  山东大学药学院/化学与化工学院 博士学位，导师：闫兵教授

2004.09-2008.06  重庆大学化学化工学院 学士学位

工作经历

2024.10-至今  国科大杭州高等研究院 副教授

2013.08-2024.09  南通大学药学院 讲师、副教授、教授

2014.07-2019.09  南京大学博士后 合作导师：朱俊杰教授

2010.09-2012.07  美国圣裘德儿童研究医院 访问学者

承担科研项目

1. 国家自然科学基，金面上项目，肠道内纳米颗粒生物分子冠的成分解析及在肠道吸收纳米颗粒中的作用研究，主持

2. 国家自然科学基金，青年项目，蛋白质冠状物对纳米载体靶向功能的影响，已结题，主持

3. 江苏省教育厅，人才项目，江苏省高校“青蓝工程”优秀青年骨干教师，已结题，主持

4. 珠江三角洲水质安全与保护教育部重点实验室，开放课题，环境中痕量致病微生物的现场快检，已结题，主持

5. 南通市科技计划项目，生物分子冠在肠道吸收口服纳米制剂中的作用研究，已结题，主持

6. 南通市科技计划项目，基于法尼基硫代水杨酸的混合胶束用于阿霉素的递送，已结题，主持

奖励及荣誉

1. 江苏省高等学校科学技术研究成果奖三等奖（2023）

2. 江苏省“青蓝工程”优秀青年骨干教师（2021）

3. 江苏省“双创计划”科技副总（2022）

4. 南通市自然科学优秀学术论文（2021）

5. 南通大学优秀教育工作者（2024）

6. 南通大学优秀硕士学位论文指导教师（2022）

代表论著

1. Y. Zhang, X. Dong, C. Jiang, Y. Yu, H. Zhang, J. Fu, G. Su*, Y. Liu*. A competitive aptamer binding-based CRISPR-cas biosensor for sensitive detection of tetracycline residues in biological samples. Talanta, 2025, 286, 127491.

2. Y. Zhu; Y. Lin; B. Gong; Y. Zhang; G. Su*; Y. Yu*. Dual Toeholds Regulated Cas12a Sensing Platform for ApoE Single Nucleotide Polymorphism Genotyping. Biosens. Bioelectron., 2024, 255, 116255.

3. S. Ren, Y. Xu, X. Dong, Q. Mu, X. Chen*, Y. Yu*, G. Su*. Nanotechnology-empowered combination therapy for rheumatoid arthritis: principles, strategies, and challenges. J. Nanobiotechnol., 2024, 22, 431.

4. J. Wang, Y. Xu, Y. Zhou, J. Zhang, J. Jia, P. Jiao, Y. Liu*, G. Su*. Modulating the toxicity of engineered nanoparticles by controlling protein corona formation: Recent advances and future prospects. Sci. Total Environ., 2024, 914, 169590.

5. G. Su, M. Xu, Y. Zhu, Y. Zhang, Y. Lin, Y. Yu*. Simultaneous and multiplexed phenotyping of circulating exosomes with orthogonal CRISPR-Cas platform. Chem. Commun., 2024, 60, 5944–5947.

6. Y. Zhang, B. Gong, Y. Lin, Y. Zhu, G. Su*, Y. Yu*. Split G-quadruplex based PfAgo sensing platform for nucleotide mutations discrimination and human genotyping. Analyst, 2024, 149, 709-711.

7. Y. Kang, J. Wang, W. Zhang, Y. Xu, B. Xu, G. Qu, Y. Yu*, B. Yan*, G. Su*. RNA extraction-free workflow integrated with a single-tube CRISPR-Cas-based colorimetric assay for rapid SARS-CoV-2 detection in different environmental matrices. J. Hazard. Mater., 2023, 454, 131487.

8. M. Xu, Y. Zhu, Y. Zhang, B. Gong, Y. Kang, G. Su*, Y. Yu*. Split G-quadruplex-programmed label-free CRISPR-Cas12a sensing system. Chem. Commun., 2023, 59, 7615-7618.

9. Q. Zhu, Q. Zhang, D. Fu, G. Su*. Polysaccharides in contact lenses: From additives to bulk materials. Carbohyd. Polym., 2023, 316, 121003.

10.Y. Kang, G. Su*, Y. Yu*, J. Cao, J. Wang, B. Yan*. CRISPR-Cas12a-based Aptasensor for On-site and Highly Sensitive Detection of Microcystin-LR in Freshwater. Environ. Sci. Technol., 2022, 56(7), 4101-4110.

11. G. Su, M. Zhu, M. Xu , Y. Zhu , Y. Zhang , H. Zhu , Feng Li*, Y. Yu*. Multiplexed lateral flow assay integrated with orthogonal CRISPR-Cas system for SARS-CoV-2 detection. Sensor. Actuat. B Chem., 2022, 371, 132537.

12. M. Zhu, J. Pan, M. Xu, J. Cao, Y. Zhu, H. Zhu, G. Su*, Y. Yu*. P53-MDM2 interaction monitoring and inhibitors potency evaluation based on CRISPR-Cas12a sensing platform. Sensor. Actuat. B Chem., 2022, 361, 131710.

13. J. Wang, G. Su*, X. Yan*, W. Zhang, J. Jia, B. Yan*. Predicting cytotoxicity of binary pollutants towards a human cell panel in environmental water by experimentation and deep learning methods. Chemosphere, 2022, 287, 132324.

14. W. S. Zhang, J. Pan, F. Li, M. Zhu, M. Xu, H. Zhu, Y. Yu*, G. Su*. Reverse-Transcription Recombinase Polymerase Amplification Coupled CRISPR-Cas12a for Facile and Highly Sensitive Colorimetric SARS-CoV-2 Detection. Anal. Chem., 2021, 93(8), 4126-4133. (Front Cover Paper) (ESI高被引论文)

15. Y. Zhang*, X. Fan, Z. Su, T. Yuan, H. Yin, H. Gu, Y. Zuo, S. Chen, H. Zhou, G. Su*. Pretreatment with metformin prevents microcystin-LR-induced tau hyperphosphorylation via mTOR-dependent PP2A and GSK-3b activation. Environ. Toxicol., 2021, 36(12), 2414-2425.

16. Y. Yu, W. S. Zhang, Y. Guo, H. Peng, M. Zhu, D. Miao, G. Su*. Engineering of exosome-triggered enzyme-powered DNA motors for highly sensitive fluorescence detection of tumor-derived exosomes. Biosens. Bioelectron., 2020, 167, 112482.

17. G. Su, M. Zhu, M. Xu, J. Pan, Y. Zhou, H. Zhou, W. S. Zhang, Y. Tong*, Y. Yu*. Fluorescence resonance energy transfer-based DNA framework assembled split G-quadruplex nanodevices for microRNA sensing. Chem. Commun., 2020, 56(88), 13583-13586.

18. D. Miao, Y. Yu*, Y. Chen, Y. Liu, G. Su*. Facile construction of i-motif DNA-conjugated gold nanostars as near-infrared and pH dual-responsive targeted drug delivery systems for combined cancer therapy. Mol. Pharmaceutics, 2020, 17(4), 1127-1138.

19. Y. Yu, Y. Zhou, M. Zhu, G. Su*, H. Deng, W. Chen*, H. Peng*. Dynamic split G-quadruplex programmed reversible nanodevice. Chem. Commun., 2019, 55(3), 389-392.

20. Y. Yu, Y. Zhou, M. Zhu, M. Liu, H. Zhu, Y. Chen, G. Su*, W. Chen*, H. Peng*. Programming split G-quadruplex with DNA nanocage and microRNA imaging in live cells. Chem. Commun., 2019, 55(35), 5131-5134.

21. Y. Yu, M. Zhou, W. Zhang, L. Huang, D. Miao, H. Zhu*, G. Su*. Rattle-type gold nanorods/porous-SiO₂ nanocomposites as near-infrared light activated drug delivery systems for cancer combined chemo-photothermal therapy. Mol. Pharmaceutics, 2019, 16(5), 1929-1938.

22. J. Wang, W. Zhang, S. Li, D. Miao, G. Qian, G. Su*. Engineering of Porous Silica Coated Gold Nanorods by Surface-protected Etching and Their Applications in Drug Loading and Combined Cancer Therapy. Langmuir, 2019, 35(44), 14238-14247.

23. G. Su, D. Miao, Y. Yu, M. Zhou, P. Jiao, X. Cao, B. Yan*, H. Zhu*. Mesoporous silica-coated gold nanostars with drug payload for combined chemo-photothermal cancer therapy. J. Drug Target., 2019, 27(2), 201-210.

24. G. Su*, H. Jiang, B. Xu, Y. Yu, X. Chen. Effects of Protein Corona on Active and Passive Targeting of Cyclic RGD Peptides Functionalized PEGylation Nanoparticles. Mol. Pharmaceutics, 2018, 15(11), 5019-5030.

25. G. Su*, H. Jiang, H. Zhu, J. Lv, G. Yang, B. Yan*, J.-J. Zhu*. Controlled Deposition of Palladium Nanodendrites on Tips of Gold Nanorods and Their Enhanced Catalytic Activity. Nanoscale, 2017, 9(34), 12494–12502.

26. G. Su^#, X. Zhou^#, H. Zhou*, Y. Li, X. Zhang, Y. Liu, D. Cao, B. Yan*. Size-Dependent Facilitation of Cancer Cell Targeting by Proteins Adsorbed on Nanoparticles. ACS Appl. Mater. Interfaces, 2016, 8(44): 30037-30047.

27. G. Su, C. Yang*, and J.-J. Zhu*. Fabrication of Gold Nanorods with Tunable Longitudinal Surface Plasmon Resonance Peaks by Reductive Dopamine. Langmuir, 2015, 31(2), 817-823.

28. G. Su, H. Zhou, Q. Mu, Y. Zhang, L. Li, P. Jiao, G. Jiang, B. Yan*. Effective surface charge density determines the electrostatic attraction between nanoparticles and cells. J. Phys. Chem. C, 2012, 116(8), 4993-4998.

29. G. Su, B. Yan*. Nano-combinatorial chemistry strategy for nanotechnology research. J. Comb. Chem., 2010, 12(2), 215-221.