陈小平 博士
邮箱：xiaopingchen@ucas.ac.cn
教育背景
2011.09-2017.01 理学博士 中国科学院上海有机化学研究所 导师：俞飚 院士
2007.09-2011.07 理学学士 南开大学 材料化学
工作经历
2022.07 - 至今 副研究员 国科大杭州高等研究院
2019.06 - 2022.06 药化部门经理 贝达药业有限公司
2017.02 - 2019.05 博士后研究 深圳大学和上海交通大学
研究领域
有机合成方法学研究，蛋白与多肽的化学修饰
药物设计与合成
复杂天然糖缀合物的合成与修饰
代表性文章：
1． Siyao Wang﹟, Qingqing Zhou﹟, Xiaoping Chen﹟, Ronghua Luo, Xueyun Li, Xinliang Liu, Liumeng Yang, Yongtang Zheng, and Ping Wang﹡. Modification of N-terminal a-Amine of Proteins via Biomimetic ortho-Quinone-Mediated Oxidation. Nat. Commun. 2021, 12, 2257. ( ﹟ co first author)
2． Xiaoping Chen﹟, Xiaosheng Luo﹟, Peng Xiao﹟, Jiaojiao Guo, Jiantao Zai, and Ping Wang﹡. Catalyst-Free Decarboxylation of Carboxylic Acids and Deoxygenation of Alcohols by Electro-Induced Radical Formation. Chem. Eur. J. 2020, 26, 3226. ( ﹟ co first author)
3． Xiaoping Chen﹟, Farong Ye﹟, Xiaosheng Luo﹟, Xueyi Liu, Jie Zhao, Siyao Wang, Qingqing Zhou, Gong Chen﹡, and Ping Wang﹡. Histidine-Specific Peptide Modification via Visible-Light-Promoted C-H Alkylation. J. Am. Chem. Soc. 2019, 141, 18230. ( ﹟ co first author)
4． Xiaoping Chen﹟, Xiaofei Shao, Wei Li, Xiaheng Zhang, and Biao Yu﹡. Total Synthesis of Echinoside A, A Representative Triterpene Glycoside of Sea Cucumbers. Angew. Chem. Int. Ed. 2017, 56, 7648.
5． Xiaoping Chen﹟, Qingling Wang, and Biao Yu﹡. Gold(I)-Catalyzed C-Glycosylation of Glycosyl ortho- Alkynyl Benzoates the Role of the Moisture Sequestered by Molecular Sieves. Chem. Commun.2016, 52, 12183.
专利：
kras g12c inhibitior and pharmaceutical use thereof. 吴颢，陈小平，路渊，余军，谢秀军。PCT/CN2020/137538.
Kras G12C抑制剂及其在医学上的应用。吴颢，陈小平，余军，路渊，何将旗， 王家炳。CN 112390796 A
