周伟平 博士
邮箱:weiping.zhou@ucas.ac.cn
教育背景
2018.10-2022.09 理学博士 Institut de Chimie des Substances Naturelles (ICSN) 导师:Dr. Arnaud Voituriez和Dr. Guillaume Vincent
2014.09-2017.06 理学硕士 华东理工大学 导师:童晓峰教授
2010.09-2014.06 理学学士 南通大学
工作经历
2026.01 - 至今 助理研究员 国科大杭州高等研究院
2022.11 - 2025.12 博士后 上海有机化学研究所
2018.04 - 2018.07 研究助理 上海药物研究所
2017.10 - 2018.03 研究助理 上海有机化学研究所
2017.06 - 2017.09 工艺研发员 常州合全药业有限公司
研究领域
1. 立体可控糖苷化策略的开发
2. 复杂糖苷化合物的合成和生物活性研究
代表性文章:
[1] Weiping Zhou, Gia Hao Huynh and Arnaud Voituriez. Asymmetric [3,3]-Sigmatropic Rearrangement for the Synthesis of Quaternary Center-Containing Polycyclic Molecules: Application to the Total Synthesis of Myrmenaphthol A. ChemistryEurope 2025, e202500274.
[2] Weiping Zhou, Ya-Qing Huang, Vincent Gandon and Arnaud Voituriez. Mechanistic Insights into the Gold(I)-Catalyzed [3,3]-Sigmatropic Rearrangement of Sulfoniums for the Formation of Chiral 1,4-Dicarbonyls or Formal α-Arylation of Carbony Compounds. Org. Chem. Front. 2024, 11, 6804-6812.
[3] Weiping Zhou,‡ Renjie Wu,‡ Jinchan Li, Dapeng Zhu and Biao Yu. A Ligand-Controlled Approach Enabling Gold(I)-Catalyzed Stereoinvertive Glycosylation with Primal Glycosyl ortho-Alkynylbenzoate Donors. J. Am. Chem. Soc. 2024, 146, 27915-27924. (‡ Contributed equally)
[4] Weiping Zhou and Arnaud Voituriez. Total Synthesis of (-)-HM-3 and (-)-HM-4 using an Asymmetric Gold-Catalyzed [3,3]-Sigmatropic Rearrangement of Sulfonium. Eur. J. Org. Chem. 2023, ejoc.202300126. “Special Collection on Asymmetric Synthesis and Catalysis”.
[5] Nazarii Sabat,‡ Weiping Zhou,‡ Vincent Gandon, Xavier Guinchard and Guillaume Vincent. Unbiased C3-Electrophilic Indoles: Triflic Acid Mediated C3-Regioselective Hydroarylation of N-H Indoles. Angew. Chem. Int. Ed. 2025, e202204400.(‡ Contributed equally)
[6] Weiping Zhou and Arnaud Voituriez. Synthesis of Cyclopentenones with C4-Quaternary Stereocenters via Stereospecific [3,3]-Sigmatropic Rearrangement and Applications in Total Synthesis of Sesquiterpenoids. J. Am. Chem. Soc. 2021, 143, 17348-17353.
[7] Weiping Zhou and Arnaud Voituriez. Gold(I)-catalyzed Synthesis of Highly Substituted 1,4-Dicarbonyl Derivatives via Sulfonium [3,3]-Sigmatropic Rearrangement. Org. Lett. 2021, 23, 247-252.
[8] Weiping Zhou, Chunjie Ni, Jiangfei Chen, Dong Wang and Xiaofeng Tong. Enantioselective Synthesis of 4H-Pyran via Amine-Catalyzed Formal (3+3) Annulation of δ-Acetoxy allenoate. Org. Lett. 2017, 19, 1890-1893.
[9] Ya-Qing Huang, Weiping Zhou, Pascal Retailleau and Arnaud Voituriez. Brønsted Acid-Catalyzed Asymmetric Synthesis of Cyclopentenones with C4-Quaternary Centers Starting from Vinyl Sulfoxides and Allenyl Ketones or Allenoates. Org. Lett. 2024, 26, 6637-6641.
[10] Bei-Bei Zhan, Kai-Sheng Xie, Qian Zhu, Weiping Zhou, Dapeng Zhu and Biao Yu. A Cu(OTf)2-Catalyzed Glycosylation with Glycosyl ortho-N-Phthalimidoylpropynyl Benzoates as Donors. Org. Lett. 2023, 25, 3841-3846.
[11] Chunjie Ni, Weiping Zhou and Xiaofeng Tong. Tertiary amine-catalyzed (3+3) annulations of δ-acetoxy allenoates: Substrate scope, synthetic application and mechanistic insight. Tetrahedron 2017, 73, 3347-3354.
所获奖项:
第四届“惠永正糖科学奖”优秀学业奖获奖(2024.12)
The 7th edition of Île-de-France Section of the French Chemical Society (SCF-IdF) PhD thesis Award (2023.10)
科研资助:
1. 2023年中国博士后科学基金第74批面上资助
2. 2025年国家自然科学基金青年科学基金项目(C类)