康麒凯 博士
电子邮箱: kangqikai@ucas.ac.cn
教育背景
2011.09—2016.07 理学博士 中国科学院上海有机化学研究所； 导师: 唐勇研究员
2007.09—2011.07 工学学士 南京理工大学化工学院
工作经历
2022.07起 副研究员 国科大杭州高等研究院
2021.08—2022.04 副研究员 西湖大学 合作导师: 石航 特聘研究员
2019.08—2021.07 博士后 西湖大学 合作导师: 石航 特聘研究员
2019.03—2019.07 助理研究员 西湖大学 合作导师: 石航 特聘研究员
2016.10—2018.12 博士后 日本京都大学 合作导师: Keiji Maruoka 教授
研究领域
发展可控自由基反应，创制功能手性小分子和大分子，具体研究方向包括 (1) 光致去外消旋化反应；(2) 聚烯烃可控自由基后修饰；(3) 废弃高分子材料升级回收。
代表性论文
1. Chenxi Wen, Zhengke Huang, Sheng-Ye Zhang, Zhimin Li, Bolong Chai, Zheng Huang*, Qi-Kai Kang*. Deracemization of C(sp3)-H Arylated Carbonyl Compounds via Asymmetric Ion-Pairing Photoredox Catalysis. J. Am. Chem. Soc. 2025, 147, 14625.
2. Shunlong He, Bolong Chai, Lan Gan, Guixia Liu, Qi-Kai Kang,* Zheng Huang*. Asymmetric Olefin Cyclopropanation Catalyzed by Pincer Ruthenium Complexes. Org. Lett. 2026, 28, 497.
3. Chenxi Wen, Ting Li, Zheng Huang*, Qi-Kai Kang*. Oxidative Dehydrogenation of Alkanes through Homogeneous Base Metal Catalysis. Chem. Rec. 2023, e202300146.
4. Jiajie Tang, Qi-Kai Kang *. Catalytic Deracemization of Benzylic Stereocenters. Synthesis 2026, accepted (invited paper).
5.Qi-Kai Kang+, Yuntong Li+, Kai Chen, Hui Zhu, Wen-Qiang Wu, Yunzhi Lin, Hang Shi*. Rhodium-Catalyzed Stereoselective Deuteration of Benzylic C–H Bonds via Reversible η6-Coordination. Angew. Chem. Int. Ed. 2022, 61, e202117381. (+Co-first author)
6. Kai Chen+, Qi-Kai Kang+, Yuntong Li, Wen-Qiang Wu, Hui Zhu, and Hang Shi*. Catalytic Amination of Phenols with Amines. J. Am. Chem. Soc. 2022, 144, 1144. (+Co-first author) (Top 1 Most Read Articles in a month)
7. Qi-Kai Kang+, Yunzhi Lin+, Yuntong Li, Lun Xu, Ke Li, and Hang Shi*. Catalytic SNAr Hydroxylation and Alkoxylation of Aryl Fluorides. Angew. Chem. Int. Ed. 2021, 60, 20391. (+Co-first author)
8. Qi-Kai Kang, Yunzhi Lin, Yuntong Li, and Hang Shi*. Ru(II)-Catalyzed Amination of Aryl Fluorides via η6-Coordination. J. Am. Chem. Soc. 2020, 142, 3706. (Virtual Issue of Outstanding Work Published in 2020 by Early Career Investigators)
9. Qi-Kai Kang, Lijia Wang, Qiong-Jie Liu, Jun-Fang Li, and Yong Tang*. Asymmetric H2O-Nucleophilic Ring Opening of D−A Cyclopropanes: Catalyst Serves as a Source of Water. J. Am. Chem. Soc. 2015, 137, 14594.
10. Qi-Kai Kang, Hang Shi*. Catalytic Hydrogen Isotope Exchange Reactions in Late-Stage Functionalization. Synlett 2021, DOI 10.1055/a-1354-0367. (Published as Cluster on the theme of Late-Stage Functionalization, invited by Benjamin List and Tobias Ritter)
11. Qi-Kai Kang, Yunzhi Lin, Yuntong Li, Hang Shi*. Transition-Metal-Catalyzed Amination of Aryl Fluorides. Synlett 2020, 31, 1135. (Published as Synpact)
12. Qi-Kai Kang, Sermadurai Selvakumar, and Keiji Maruoka*. Asymmetric Synthesis of α-Amino Acids by Organocatalytic Biomimetic Transamination. Org. Lett., 2019, 21, 2294.
13. Qi-Kai Kang, Sermadurai Selvakumar, Natarajan Arumugam, Abdulrahman I. Almansour, Raju Suresh Kumar, and Keiji Maruoka*. Enantioselective Alkylation of N-Arylhydrazones Derived from a-Keto Esters and Isatin Derivatives through Asymmetric Phase Transfer Catalysis. Chem. Asian J. 2018, 13, 1780.
14. Qi-Kai Kang, Lijia Wang, Zhong-Bo Zheng, Jun-Fang Li*, and Yong Tang*. Sidearm as a Control in the Asymmetric Ring Opening Reaction of Donor-Acceptor Cyclopropane. Chin. J. Chem. 2014, 32, 669.
15. Sermadurai Selvakumar, Qi-Kai Kang, Natarajan Arumugam , Abdulrahman I. Almansour , Raju Suresh Kumar, Keiji Maruoka*. Hypervalent iodine(III) catalyzed radical hydroacylation of chiral alkylidenemalonates with aliphatic aldehydes under photolysis. Tetrahedron 2017, 73, 5841.
16. Qiong-Jie Liu, Lijia Wang, Qi-Kai Kang, X. Peter Zhang*, and Yong Tang*. Cy-SaBOX/Copper(II)-Catalyzed Highly Diastereo- and Enantioselective Synthesis of Bicyclic N,O Acetals. Angew. Chem. Int. Ed. 2016, 55, 9220.
17. Feng Li*, Lin Chen, Qi-Kai Kang, Jianguang Cai and Guangjun Zhu. Regioselective N-alkylation with alcohols for the preparation of 2-(N-alkylamino)quinazolines and 2-(N-alkylamino)pyrimidines. New J. Chem., 2013, 37, 624.
18. Feng Li*, Qi-Kai Kang, Haixia Shan, Lin Chen, and Jianjiang Xie. Regioselective N-Alkylation of 2-Aminoimidazoles with Alcohols to 2-(N-Alkylamino)imidazoles Catalyzed by the [Cp*IrCl2]2/K2CO3 System. Eur.J.Org.Chem. 2012, 5085.
19. Feng Li*, Haixia Shan, Lin Chen, Qi-Kai Kang and Po Zou. Direct N-alkylation of amino-azoles with alcohols catalyzed by an iridium complex/base system. Chem. Commun., 2012, 48, 603.
20. Feng Li*, Haixia Shan, Qi-Kai Kang and Lin Chen. Regioselective N-alkylation of 2-aminobenzothiazoles with benzylic alcohols. Chem. Commun., 2011, 47, 5058.
专利
1. 石航，康麒凯，李运通；一种芳环苄位碳氢键选择性氘代的方法；专利申请号：202110863225X。
2. 唐勇，胡江林，谢作伟，康麒凯，刘琼杰，程雨晶；具有光学活性的环己基噁唑啉配体的合成方法及其用途；授权公告号：CN104926747B。
