占贝贝

占贝贝  博士

Email：zhanbeibei@ucas.ac.cn

学习及工作经历

2022.08-至今 国科大杭州高等研究院特聘副研究员

2020.07-2022.07，国科大杭州高等研究院博士后 （合作导师：俞飚院士）

2015.09-2020.06，浙江大学，理学博士 （导师：史炳锋教授）

2011.09-2015.06，浙江工业大学，工学学士

研究领域：

1. 金属有机化学/不对称催化

2. 新型糖苷化反应的设计与应用

3. 可见光催化

代表性论文：

• B. Zhang^†, H. Bai^†, B.-B. Zhan^†*, K. Wei, S. Nie*, X, Zhang*. Deacylative arylation and alkynylation of unstrained ketones. Science Advances 2024, 10, eado0225. (共同通讯作者)

• L. Bao, H. Yang, B.-B. Zhan*, X, Zhang*. Photoinduced Bi-catalyzed C–H trifluoromethylation of (hetero)arenes. Chem Catal. 2024, 4, 100877. (共同通讯作者)

• B.-B. Zhan, K.-S. Xie, Q. Zhu, D. Zhu, B. Yu*, A Cu(OTf)₂-Catalyzed Glycosylation with Glycosyl ortho-N-Phthalimidoylpropynyl Benzoates as Donors. Org. Lett. 2023, 25, 5372-5377.

• B.-B. Zhan, L. Jin, B.-F. Shi*, Palladium-Catalyzed Enantioselective C−H Functionalization via C−H Palladation. Trends in Chem. 2022, 4, 220-235.  

• B.-B. Zhan, Z.-S. Jia, J. Luo, L. Jin, X.-F. Lin, B.-F. Shi*, Palladium-Catalyzed Directed Atroposelective C−H Allylation via β-H Elimination: 1,1-Disubstituted Alkenes as Allyl Surrogates. Org. Lett. 2020, 22, 9693-9698.

• B.-B. Zhan, M.-X. Jiang, B.-F. Shi*, Late-Stage Funcationalization of Peptides via Palladium-Catalyzed C(sp³)−H Activation Strategy. Chem. Commun. 2020, 56, 13950-13958.

• B.-B. Zhan, L. Wang, X.-F. Lin, B.-F. Shi*, Synthesis of Axially Chiral Biaryl-2-amines via Pd(II)-Catalyzed Free Amine-Directed Atroposelective C−H Olefination. Angew. Chem. Int. Ed. 2020, 59, 3568-3572.

• B.-B. Zhan, J. Fan, L. Jin, B.-F. Shi*, Divergent Synthesis of Silicon-Containing Peptides via Pd-Catalyzed Post-Assembly γ-C(sp³)−H Silylation. ACS Catal. 2019, 9, 3298-3303.

• B.-B. Zhan, Y. Li, J.-W. Xu, J. Fan, L. Jin, B.-F. Shi*, Site-Selective δ-C(sp³)−H Alkylation of Amino Acids and Peptides with Maleimides via a Six-Membered Palladacycle. Angew. Chem. Int. Ed. 2018, 57, 5858-5862 (Hot paper).

• B.-B. Zhan, Y.-H. Liu, B.-F. Shi*, Nickel-Catalyzed ortho-Halogenation of Unactivated (Hetero)aryl C−H Bonds with Lithium Halides Using a Removable Auxiliary. Chem. Commun. 2016, 52, 4934-4937.

专利

1. 张夏衡; 占贝贝; 尉凯航 ; 一种可见光诱导酮的脱酰化制备烯烃的反应方法, 2024-03-20, 中国, CN202410319453.4

2. 张夏衡; 占贝贝; 张博一; 杨鸿向 ; 二氢三氮唑芳构化前体及其在酮的脱酰芳基化反应中的应用, 2023-12-28, 中国, CN202311836345.6

所获奖励

浙江省优秀毕业生、浙江大学优秀毕业生、浙江省化学会创新奖二等奖、TET Best Poster Award 2019、国家奖学金等

科研项目

1. 国家自然科学基金青年项目

2. 杭高院人才启动经费

3. 杭州市领军型创新创业团队项目