姓名:刘念 |
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性别:女 |
职称:讲师
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邮箱:liunian@ucas.ac.cn |
研究方向:外源金属的微观赋存特征及健康效应分析,单颗粒和单细胞检测方法开发及优化 |
教育经历:
2015.08-2021.06 中国科学院大学,中国科学院生态环境研究中心,环境科学专业,博士学位,导师:何滨、胡立刚、曲广波 研究员
2011.08-2015.06 中国农业大学,理学院,化学专业,学士学位
工作经历:
2023.09-至今 国科大杭州高等研究院 讲师
2021.07-2023.09 国科大杭州高等研究院,环境学院,博士后
承担科研项目:
1. 国家自然科学基金,青年基金,22206033,幼鼠海马体中铅赋存的单细胞图谱研究,2023年1月–2025年12月,资助经费30万元,主持
2. 中国博士后科学基金,第71批面上资助二等,2022M713303,人群精子中外源金属赋存的单细胞图谱研究,2022年8月–2024年8月,资助经费8万元,主持
3. 国家自然科学基金,重大项目/课题申请,22193052,生命过程中外源污染物的识别与追踪,2022年1月–2026年12月,资助经费431万元,参与
代表论著:
1. Liu, N.#; Huang, Y.#; Zhang, H.; Wang, T.; Tao, C.; Zhang, A.; Chen, B.; Yin, Y.; Song, M.; Qu, G.; Liang, Y.; Shi, J.; He, B.; Hu, L.*; Jiang, G., Unified probability distribution and dynamics of lead contents in human erythrocytes revealed by single-cell analysis. Environmental Science & Technology 2021, 55 (6), 3819-3826.
2. Liu, N.; Li, Y.; Liu, L.; Liu, X.; Yin, Y.; Qu, G.; Shi, J.; Song, M.; He, B.; Hu, L.*; Jiang, G., Administration of silver nasal spray leads to nanoparticle accumulation in rat brain tissues. Environmental Science & Technology 2022, 56 (1), 403-413.
3. Liu, N. #, Chen, H. #, Li, Y., Zhang, G., Zhang, J., Qu, G., He, b., Meng, T., Xiong, C., Pan, A., Yin, Y., Lian, Y., Wan, Y.*, Hu, L.*, and Jiang, G., Exogenous metals atlas in spermatozoa at single-cell resolution in relation to human semen quality. Environmental Science & Technology 2023, 57 (19), 7358-7369.
4. Liu, N.; Qu, G.; Wen, R.; Liu, X.; Wang, Y.; Gao, J.; Yin, Y.; Shi, J.; Zhou, Q.; He, B.*; Hu, L.*; Jiang, G., Occurrence of silver-containing particles in rat brains upon intranasal exposure of silver nanoparticles. Metallomics 2022, 14 (1), mfab077.
5. Sun, Y.#; Liu, N.#; Wang, Y.; Yin, Y.; Qu, G.; Shi, J.; Song, M.; Hu, L.*; He, B.; Liu, G.; Cai, Y.; Liang, Y.; Jiang, G., Monitoring AuNP dynamics in the blood of a single mouse using single particle inductively coupled plasma mass spectrometry with an ultralow-volume high-efficiency introduction system. Analytical Chemistry 2020, 92 (22), 14872-14877.
6. He, Q.#; Lu, J.#; Liu, N.#; Lu, W.; Li, Y.; Shang, C.; Li, X.; Hu, L.*; Jiang, G., Antiviral properties of silver nanoparticles against SARS-CoV-2: Effects of surface coating and particle size. Nanomaterials 2022, 12 (6), 990.
7. 刘念,王园园,胡新笑,何滨,曲广波,史建波,胡立刚*,江桂斌.单细胞分析技术在人类细胞图谱计划中的应用.中国科学:化学,2018, 48 (10), 1217-1225.
8. Zhou, Q.; Liu, L.; Liu, N.; He, B.; Hu, L.*; Wang, L., Determination and characterization of metal nanoparticles in clams and oysters. Ecotoxicology and Environmental Safety 2020, 198, 110670.
9. Wu, Q.; Shi, J.; Ji, X.; Xia, T.; Zeng, L.; Li, G.; Wang, Y.; Gao, J.; Yao, L.; Ma, J.; Liu, X.; Liu, N.; Hu, L.; He, B.; Liang, Y.; Qu, G.; Jiang, G., Heterogenous internalization of nanoparticles at ultra-trace concentration in environmental individual unicellular organisms unveiled by single-cell mass cytometry. ACS nano 2020, 14 (10), 12828-12839.
10. Yang, Q.; Cheng, M.; Zhou, Q.; Wang, L.; Jiao, Y.; Liu, Y.; Zhang, S.; Tan, L.; Gu, Z.; Zhu, H.; Luo, H.; Lin, D.; Liu, N.; Huang, X.; Hu, L., Sharply and simultaneously increasing pollutant accumulations in cells of organisms induced by rare earth elements in the environment of Nanjing. Chemosphere 2023, 311, 136823.
11. 刘志东,刘念,农骐郢,李裕,刘晓蕾,赵娜,王婷,黄永顺,何滨,胡立刚,铅中毒患者驱铅治疗效果的影响因素,环境化学,2023. (Accepted)
申请或授权专利:
1. 胡立刚,刘念,王丁一,曲广波,何滨,江桂斌,一种用于单个红细胞中元素检测的试剂盒及其检测方法,专利申请号:202010009183.9(已受理)
2. 胡立刚,刘念,何滨,江桂斌,一种单细胞水平上无机元素暴露与精液质量关联性的检测方法,专利申请号:202310105081.0(已受理)
3. 胡立刚, 霍诗薇, 刘念, 江桂斌. 一种单细胞水平上铅含量分布模型的拟合方法,专利申请号:2023101359311(已受理)
4. 胡立刚,孙玉贞,刘念,王丁一,刘丽红,何滨,江桂斌,一种用于sp-ICPMS联用的高通量微量进样系统,专利号:ZL2018021486969.4(已授权)